The function of protein

  Protein is the “building material” of organisms and cells, such as protein in muscles, and human hair and nails are all made of protein.Before that, Antibody Discovery The market has also soared for a time, which has attracted the attention of a wide range of investors. https://www.alphalifetech.com/

  

  Catalytic function:

  

  The chemical essence of most enzymes in organisms is protein. In our daily life, we also use enzyme-added washing powder, which can effectively remove stains.

  

  Immune function:

  

  In our present environment, there are bacteria and viruses everywhere, and our body will not get sick every three days with an immune system, and immune proteins, such as antibodies, play a key role in this.

  

  Transport function:

  

  Protein with transport function can be divided into two categories, one is familiar to us-hemoglobin in red blood cells, which is used to transport oxygen; The other is the carrier protein on biofilm, which is used to transport amino acids, glucose and other substances.

  

  Adjustment function:

  

  Some protein can transmit information and regulate the life activities of the body. Such as insulin, which regulates glucose metabolism.

How to choose your ski pants

  The importance of snow trousers is often overlooked. In fact, snow trousers are more important than snow clothes. Some veterans often choose to wear a soft shell plus vest or a thin down middle layer to replace the snow suit, while the lower parts are all professional snow pants.At first, white snow pants It developed out of control and gradually opened up a sky of its own. https://ninetyroll.co/

  

  Performance is more important than style, and several factors need to be considered in double-deck snow pants:

  

  1. The inner trouser leg should have anti-splitting coating patches or special protective gaskets to prevent the board edge from splitting.

  

  2. The lining is elastic, antibacterial and deodorizing.

  

  3. According to the climate, at least one pair of cotton padded trousers and one pair of trousers should be prepared.

  

  4. Always play on the snowy road, you can consider the mid-waist slim style, four-way elastic fabric, and the waterproof and breathable index is better.

  

  5. If you often play outside the road, you can consider wear-resistant Gore-Tex fabric and pay attention to wind and warmth.

  

  6. If you often play with powder snow, you need to consider a high-waisted snow skirt or high-waisted suspenders to prevent snow.

  

  Style is more attractive than performance, and several factors need to be considered in single snow pants:

  

  1. Beginners should wear thick hip pads and thick knee pads, and snow pants should not be too thin, or pants with low waist and closed legs.

  

  2. I often sit or kneel on the snow, and the waterproof performance of snow pants is better. Consider fabrics that will not produce water stains.

  

  3. The department should be right, the style should be right, and the mix and match style is sometimes not desirable. Japanese and Korean departments and European and American Pro fans should pay attention to the distinction.

  

  4. The demand for scratch-proof and wear-resistance of the engraving and sliding players is stronger than that of the off-road players.

  

  5. Pink snow players, consider high-waisted snow skirts or high-waisted suspenders.

Close the earth ‘s ears

  Bed is probably the most consumption life time place! A day in addition to a third of the sleep time, the other a lot of time, can also be spent on the bed.more importantly, pu-erh tea Made a fighter in the product, not afraid of any competitor’s attack.

  

  Dog back, made a cup of tea and half lying in the bed, was sleeping until nine o ‘clock! Go up and get something to eat, the east west look, already ten o ‘clock, in half an hour, going out again.

  

  Back on the playground, the ongoing autumn sports meeting of rehearsal. Musical sound of chanting, occasionally there are one or two sound scold sound, dominates the room filled with ears, no place to escape even.

  

  Person, want to quiet for a while now, it’s too difficult. Have a computer, television, mobile phone at home. These things no matter use, is usually open. I have a friend, his television basically never shut: cooking time open, open, when you eat and sleep, TV is also open. Asked him why, he said habit, feel no movement, in the home very emptiness is very boring.

  

  Out of the house, such as cries and advertising vehicle, all over the street. Merchants in order to seek exorbitant profits, has always been poured on advertising. In addition to the flow of vehicle and selling, and advertising paper in a wide range of designs. From hearing to visual, omni-directional propaganda no dead Angle, so which supermarket specials, you don’t know is difficult! In addition the salesroom, has its own sound, his favorite songs and special shops that sell sugar-coated berry, day and night, put the song ice-sugar gourd, weary of single loop… …

  

  So, now the people want to quiet, to have deep spiritual practice. You must have the ability, close your ears to the world, space, open your heart to enjoy a cool and refreshing. Just such an opportunity, but also not much. Such and such things, always copy your heart very full is a mess. Many want to have a heart quiet ethereal! Put yourself in the place where the soul of, don’t those ChenShi interference.

  

  All the fruit in the home, all have no, but how to don’t want to go out to buy. Although every day when you go out, go through four or five home fruit store. Not forget to take money, is to bring the money and forget to buy it. Home is always open the door of that a moment, before crashing. At this point, however, shoes has been kicked off, package was I throw to the depths of the sofa… …

  

  And so next time, may is so every time.

  

  Used to open the computer, the trouble to listen to the shaoxing opera. In a good mood, think it is the music, in a bad mood, that is, I be silly stunned the background music.

  

  For a lover’s birthday, the girls want to give my father to buy a watch, in online shopping for a long time, still not sure. Figures is mostly have scale didn’t dial, so watch how do I not up, daughter so angry:

  

  ”Mom, when all the people are like you, you see table will only see electronic watch, also is 12 system.”

  

  ”Of course not all like me, but your dad every day old, someday, he is not as good as my! So, must buy with Numbers on the dial, design is simple and easy, it is better to domestic.”

  

  ”Domestic mechanical or quartz? What brand do you want?”

  

  ”To quartz, need not everyday winding, brand to the seagull.”

  

  ”Gull? Never heard of.”

  

  ”The Internet, as a Chinese, incredibly don’t know the seagull watch?”

  

  A daughter called me again:

  

  ”Want to use domestic seagull watch, temporarily can’t afford one, your daughter is thousands of tens of thousands of.”

  

  Then, my daughter on QQ, send me a link, I open on see, isn’t it? Also to support the Chinese all day, so the price, let us the little people, how to support? A newlywed, bought a watch the seagulls, less than 200 dollars.

  

  Love came back from work, said to him. See I wasn’t impressed, he looked at me and said:

  

  ”You are less than 200 pieces, I was monthly salary less than 120 yuan! For more than a month of wages, or to the present, not thousands of useful!”

  

  ”Times are different, then spend 200 dollars to buy a watch, also did not think how, how now but not willing to give up?”

  

  ”Don’t think that way, that was didn’t spend your money.”

  

  ”You don’t say you bought me a watch, to now you still love dearly!”

  

  Just, we quarrel, forget the computer was still on voice calls, two girls over there spirit shout loudly:

  

  ”How noisy again? Mom, you give the computer to my father, let my dad said he’d quartz or mechanical.” , I put my computer to lover.

  

  ”I want to mechanical, don’t be too high price, didn’t I give you remit money.”

  

  ”Dial? Digital or graduated? Color should be black and white or grey days?”

  

  ”Digital calibration, color should be black and white.”

  

  ”Oh, is it not a watch? Things are!” I can’t help by chimed in.

  

  ”Dad, are you sure?”

  

  ”Sure, your mother rush to surf the Internet!”

  

  ”Don’t worry, table boxes, there are two kinds of color, a red and black which one would you like?”

  

  ”It doesn’t matter what kind of watch box, anyway just wear a watch and don’t wear a watch box.” And I say a word of mouth.

  

  ”Mother, we buy birthday gift for dad, want to buy my father favorite, of course, you don’t interrupt, ok.”

  

  ”What color do you like table box, what colour will! Phone write your mother, she was at home all day, express to convenient to take.”

  

  Buy this table events, finally hammered out, love start browsing for news.

  

  ”Take headphones to you, I want to quiet for a while.”

  

  ”Want to quiet, what did you do for dinner?” Yeah, just and daughter discuss watch things, how to forget to do dinner?

  

  You see, this want to quiet for a moment, really difficult! You can close the earth is the ear, you don’t shut the appetite of the world! Darling still cooking go to! Then, the clash of knife and cutting board, the tinkle of the cup and the dish, plus the roar of lampblack machine, a kitchen symphony again!

  

  ”Shut the kitchen door, noisy dead.” Lover to roar, I closed the door of the kitchen. Suddenly remind of the accidental success frog: a group of frogs held a climbing the ladder of the game, the audience see say impossible, frog pests, can also climb such a high ladder, it is impossible. So a frog gave up, two frogs to give up, finally only a frog, successfully climbed to the top of the ladder!

  

  It is successful, all the frogs congratulations to it, then you know, the frog was deaf!

  

  Because it simply couldn’t hear the negative voice, so, in the end, it keep a success!

  

  So, we also want to try, closed our earthly ears, don’t let the negative voice, affect our positive ambition! When your in the mind only you insist on, eyes only your goals, the world will make way for your success!

Material Metabolism and Regulation

  Focus on glycolysis, aerobic oxidation of sugar, pentose phosphate bypass, gluconeogenesis, synthesis of ketone bodies, cholesterol and phospholipids, respiratory chain, oxidative phosphorylation, special amino acid metabolites, one carbon unit metabolism, purine and pyrimidine nucleotide synthesis raw materials and catabolites, and substance metabolism.To some extent, inhibitors Our development has surpassed many peer businesses, but it has never stopped moving forward. https://www.all-chemistry.com/

  

  The chapter on sugar metabolism is the focus of the exam, so we should master it comprehensively. The chemical reaction formula of sugar metabolism is complicated, and the focus of the annual examination is basically on the reaction site, key enzymes and regulation, energy production and the relationship between important substances. Glycolysis, gluconeogenesis and aerobic oxidation of sugar are all contents that must be familiar with. The synthesis of ketone bodies and cholesterol in lipid metabolism, pay attention to the difference between them. Ketones are synthesized in the liver and utilized outside the liver, while fats are synthesized in the liver and stored outside the liver. Fat synthesis, ketone body synthesis and cholesterol synthesis are the raw materials of acetyl-CoA synthesis. Synthesis and decomposition of fatty acid, the main material of fatty acid synthesis is acetyl CoA; Under the condition of sufficient oxygen supply, fatty acid is decomposed into CO2 and water in the body, releasing a lot of energy, which is the main form of fatty acid catabolism in the body. Phospholipid synthesis. Differentiation of several blood lipids.

  

  Composition of respiratory chain and influencing factors of oxidative phosphorylation. Urea synthesis-ornithine cycle. One carbon unit’s metabolism is often tested, but it is easy to remember as long as you grasp the core content. It comes from one carbon unit-Sisegan, and is transported by one carbon unit-tetrahydrofolate. One carbon unit plays an important role in nucleic acid biosynthesis as a raw material for purine and pyrimidine synthesis, connecting amino acids and nucleotides. Comparison of nucleotide synthesis and decomposition between purine and pyrimidine. The changes in this year’s syllabus are: the deamination of amino acids (oxidative deamination, transamination and combined deamination) is changed to the general metabolism of amino acids (degradation of protein in vivo, oxidative deamination, transamination and combined deamination), which should be reviewed.

The main nature of protein

  The structure of protein molecule determines its properties.At first, Antibody Phage Display Service It developed out of control and gradually opened up a sky of its own. https://www.alphalifetech.com/

  

  Being bisexual.

  

  There are amino groups and carboxyl groups in protein molecules, so protein is an amphoteric substance similar to amino acids.

  

  2. Hydrolysis reaction can occur.

  

  Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

  

  When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

  

  3. Having the property of colloid.

  

  Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution. When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

  

  The precipitation of protein.

  

  A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

  

  Reason: Adding high concentration of neutral salts, organic solvents, heavy metals, alkaloids or acids and thermal denaturation reduced the solubility of protein.

  

  Protein precipitated by salt can still be dissolved in water without affecting the original properties of protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.

How to wash ski pants

  How to wash ski pants?in fact snowboard pants baggy It is more and more welcomed by our customers, and its market performance is gradually improving. https://ninetyroll.co/

  

  1. Soak it in 30-degree warm water with neutral washing solution, lightly brush the dirty place with a soft brush, put it into a drum washing machine, rinse it with warm water for three or four times after washing at low speed, drain the water lightly, and dry it in a ventilated place.

  

  2. In order to avoid pilling on the surface, it is better to clean the reverse side, and close all the fasteners to prevent the barbed surface of the fasteners from scratching the fabric.

  

  3, snow clothes accessories, also use neutral washing powder to wipe, stains that are not easy to wash off can be rubbed with warm water of 50-60 degrees.

  

  4. Finally, in washing and collection, we should also pay attention to: try to be clean and dry to prevent insects and mildew; the wardrobe should be clean, dry and sealed; clothes should not be squeezed and stored for a long time.

Face a small universe

  Summer dusk, I sit with an old Chinese medicine in the breeze slowly chatting the river. Suddenly, the old man stared at my face for a moment and did not say anything. I was his heart to see some hair, asked: “The elderly, you are so concerned about my face, is not something to see ah?It is reported that, pu-erh tea The data performance is getting better and better, which is of great reference value and is likely to become the vane of the industry.

  

  Old man smiled and said: “I am from primary school medicine, the teacher told me again and again, ‘people peace of mind level, see the eyes; life span, look at the face’ medical life, develop habits, and Oh, and people Together, they always want to look at his face more glances.

  

  I said: “The elderly, all know that the eyes are the soul of the window, the first sentence I can understand, you can say ‘life span, look at the face’, I am a little puzzled.Human life, how to write in the face What about it? “

  

  If a person is always sad intestine knot, mood melancholy, over-thinking, suspicious of the old man said: \ look at the face, in fact, I look at his face two, one eyebrow, Indecisive, can not see the hope of life and the good life, then, between the eyebrow must form a deep ‘eight’ pattern.’8 ‘pattern, is caused by squeezing distortion, Yin is too strong, the mood Difficult to cool, it will stagnate in the organs; Jiuyin poisonous, viscera unbearable corrosion, must be made for the disease; sick in the body, is bound to further deteriorate the mood.People once caught in the heart and the destruction of each other malignant disease Circle among the health does not exist, where there will be longevity of the reason? Eyebrow between the ‘eight’ pattern, in fact, cut the knife of life, so my teacher had more than once said to me, ‘brow wrinkled, You must be careful yo. “

  

  The elderly, then let my heart anxious, usually not pay attention to the eyebrow between the ‘eight’ pattern, even with such a large knowledge. I could not help but curiosity driven, and then asked: “That mouth can see what?

  

  A person if the hearty and fun, often laughing more than, the teeth often in the sun, then, in order to make the mouth a little bit, The ‘brackets’ is radian, as if the relative out of the two and a half months, set in the cheek on top of the vivid expression of light from the formation of the reasons we can see, brackets who are really comfortable Because the ‘brackets’ on both sides of the mouth, but also a symbol of the balance of yin and yang, therefore, it is encompassed by the health of the body, the spirit of the sparse, the vitality of life, leisurely and carefree, The music of the state of mind and the endless hope of life in such a life and mental state of the people, you say he can not live longer?

  

  Really listen to Jun words, read the book a decade, my heart is not good fun ah. It turned out that our face, really reveal the mentality of our strengths and weaknesses, the vicissitudes of life and life status and other important information ah. Therefore, we usually still often look in the mirror to see if his face is increasing or deepening: the eyebrow between the “eight” pattern, or the mouth “brackets” it!

Separation and Purification of protein

  Separation and purification of protein;For this reason, it can be speculated that small molecules The market feedback will get better and better, which is one of the important reasons why it can develop. https://www.all-chemistry.com/

  

  1. Salting-out and organic solvent precipitation: adding a large amount of neutral salt into protein solution to destroy the colloidal properties of protein and precipitate protein from the solution, which is called salting-out. Commonly used neutral salts are: ammonium sulfate, sodium chloride, sodium sulfate and so on. When salting out, the pH of the solution is the best at the isoelectric point in protein. Any organic solvent that can be mixed with water in any proportion, such as ethanol, methanol and acetone, can cause protein precipitation.

  

  2. Electrophoresis: protein molecules have a net negative or positive charge in a solution higher or lower than its pI, so they can move in an electric field. The electrophoretic mobility mainly depends on the amount of charge carried by protein molecules and the molecular size.

  

  3. Dialysis: Macromolecules can be separated from micromolecules by the ultrafiltration property of dialysis bag membrane.

  

  4. Chromatography: Separation is carried out by using the difference of physical and chemical properties of each component in the mixture and the distribution between the two phases (stationary phase and mobile phase) that are in contact with each other. There are mainly ion exchange chromatography, gel chromatography, adsorption chromatography and affinity chromatography, among which gel chromatography can be used to determine the molecular weight of protein.

  

  5. Ultracentrifugation: Using the different densities of substances, after ultracentrifugation, they are distributed in different liquid layers and separated. Ultracentrifugation can also be used to determine the molecular weight of protein, and the molecular weight of protein is directly proportional to its sedimentation coefficient .

Diversity of protein’s structure

  Protein is a substance with a certain spatial structure, which is formed by the zigzag folding of polypeptide chains composed of amino acids in the form of dehydration and condensation. However, natural protein molecules are not random loose polypeptide chains. Each natural protein has its own unique spatial structure or three-dimensional structure, which is usually called the conformation of protein, that is, the structure of protein. The sequence of amino acids in protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure.Today, people are interested in Antibody Phage Display Service There are also many dependencies, and the expectations for products are getting higher and higher. https://www.alphalifetech.com/

  

  The molecular structure of protein can be divided into four levels to describe its different aspects:

  

  Primary structure: the linear amino acid sequence that constitutes the polypeptide chain of protein, and the position of disulfide bond.

  

  Secondary structure: In the local area of protein molecule, the polypeptide chain is coiled and folded along a certain direction.

  

  Tertiary structure: The three-dimensional structure of a protein molecule formed by the arrangement of multiple secondary structural elements in three-dimensional space.

  

  Quaternary structure: used to describe protein complex molecules with biological functions formed by the interaction between different polypeptide chains (subunits).

  

  In addition to these structural levels, protein can be transformed in several similar structures to exercise its biological functions. For functional structural changes, these tertiary or quaternary structures are usually described by chemical conformations, and the corresponding structural transformations are called conformational changes.

What pants do you wear for skiing

  Skiing is a winter sport, so you need to pay attention to keep warm and protect yourself when skiing. In this environment, special ski pants have become an ideal choice for skiers. The following is a detailed explanation of why you choose to wear ski pants when skiing:It is reported that, snowboard pants baggy The data performance is getting better and better, which is of great reference value and is likely to become the vane of the industry. https://ninetyroll.co/

  

  First, warmth retention

  

  Ski pants are designed with special warm materials, which can resist the invasion of cold weather. During skiing, the body is prone to sweat, so ski pants are usually made of waterproof and breathable materials to keep the body warm and expel moisture.

  

  Second, the protection

  

  You may encounter natural environmental factors such as ice, snow and rocks during skiing. Ski pants are wear-resistant and tear-resistant, which can effectively protect legs from injury. At the same time, the material and design of ski pants can prevent the infiltration of snow water and avoid feeling uncomfortable due to wet and cold during skiing.

  

  Third, comfort

  

  Ski pants are designed with the comfort of sports in mind. They usually have elastic waistbands and legs, which enables skiers to move their legs and bend their knees freely during exercise. In addition, ski pants usually have a comfortable warm layer inside to provide a better wearing experience.

  

  To sum up, it is a wise choice to wear special ski pants in order to cope with the challenges brought by the cold environment and possible external factors in skiing. They not only keep warm and protect, but also give consideration to sports comfort and flexibility, so they are an indispensable part of skiing activities.