I. AnswersThe above conclusions show that Azilian lifemotion To a great extent, it can bring new vitality to the market and make the industry develop well. https://www.azilian.co

　　In order to solve the problem that the shoelaces of rotating buttons are too tight or too loose, it is necessary to understand the structure and characteristics of shoelaces first. Usually, just gently adjust the knob on the button up or down. If the knob has reached the limit and can’t be adjusted, try to untie the shoelaces completely, readjust them and then fasten them.

　　Second, the analysis shows that

　　Characteristics of rotating button shoelaces

　　Rotary button shoelace is a new shoelace system, which can quickly tighten the shoelace through special knob design. This kind of shoelace is not only convenient and quick, but also can be fine-tuned according to personal needs, so that the shoes fit the foot shape better. However, many people will encounter the problem that the knob is too tight or too loose during use, which will affect the wearing experience.

　　Adjustment method of knob tightness

　　(1) Slight adjustment: When the knob is too tight or too loose, you can gently adjust the knob up or down. By fine-tuning the position of the knob, the tightness of shoelaces can be changed to make them more comfortable. Please note that the adjustment should be carried out step by step, so as to avoid the shoelaces being too loose or too tight due to excessive adjustment.

　　(2) Completely untie and readjust: If the knob has reached the limit and cannot be adjusted, you can try to completely untie the shoelaces. Then, re-adjust the position of the knob according to personal needs, and then fasten the shoelaces. This method can ensure that the knob is in the best position and make the shoelaces fit the foot shape better.

　　matters need attention

　　(1) When adjusting the tightness of the knob, keep the knob dry and clean. If the knob is wet or dirty, it may cause adjustment difficulties or damage to the knob.

　　(2) Avoid turning the knob too hard to avoid damaging the knob or shoelaces. It should be adjusted gently to achieve the best tightness.

　　(3) Regularly check the wear of knobs and shoelaces. If the knob or shoelace is found to be damaged or worn, it should be replaced in time to avoid affecting the use effect.

　　Third, the actual operation steps

　　First, observe the position of the knob. If the knob is too tight or too loose, it needs to be adjusted accordingly.

　　Gently adjust the knob up or down with your fingers. Pay attention to it step by step to avoid over-adjustment.

　　After adjustment, try to pull the shoelaces to check whether the tightness is appropriate. If it is still not suitable, continue to make adjustments.

　　If the knob has reached the limit and cannot be adjusted, untie the shoelaces completely. Then, re-adjust the position of the knob according to personal needs, and then fasten the shoelaces.

　　Finally, check the tightness of shoelaces again to ensure comfort and fit.

　　IV. Summary and Prospect

　　Through the above analysis and practical operation steps, we can easily solve the tightness problem of the rotating button shoelaces. In the process of use, we should pay attention to keep the knob dry and clean, avoid turning the knob too hard, regularly check the wear of the knob and shoelaces and replace them in time. Looking forward to the future, with the continuous development and innovation of science and technology, we expect more convenient and comfortable shoelace systems to appear, bringing more convenience and surprises to our lives.

　　Most protein is like a jumble of atoms packed together. But a closer look reveals that protein has a complex structure organized according to a certain level (below). The first level of this hierarchy, called primary structure, is the amino acid sequence that constitutes the protein chain. Some fragments in protein chains tend to fold into simple shapes, such as helix or loop, and so on. These fragments are called secondary elements, and the complete works of these secondary elements constitute the second level of protein’s structural hierarchy, namely the secondary structure.In order to facilitate users to have a better experience, recombinant proteins Many attempts have been made to upgrade the products, and the results are also very good, and the market performance tends to be in a good state. https://www.alphalifetech.com/

　　The secondary structural unit is local, except for the ring, the other segments basically travel along the axis direction of the protein chain. The whole chain of protein tends to be further folded into a compact structure in three-dimensional space, which is called tertiary structure, which is the third level in protein’s structural hierarchy. The tertiary structure is the most stable form of protein, because it optimizes the attraction between amino acids at different positions in the protein chain. Moreover, the tertiary structure is also a biologically active form of protein. If this form is destroyed, protein will lose some or all of its functions. Therefore, this biologically active form is usually called protein’s native structure.

　　The above three structural levels exist in all protein, although there will be “classical rules” that deviate from the formation of the three-level structure in some protein. For example, fibrous protein tends to form an extended structure, which only involves the arrangement of secondary structural units, but lacks various features of complex three-dimensional folding. Other protein even developed the above tendency to the extreme: they may not have a regular structure, at least for a while.

　　Organic chemistry is an important branch of studying carbon compounds, involving the source, structure, properties and other aspects of organic matter, and providing revelation for the material basis of life phenomena. It plays a key role in medicine, industrial production and other fields, but it still faces challenges such as green synthesis and drug molecular selectivity. Organic chemists are constantly exploring new reaction mechanisms and synthetic methods to promote the development of the discipline.To some extent, inhibitors Our development has surpassed many peer businesses, but it has never stopped moving forward. https://www.all-chemistry.com/

　　Generated by the author through intelligent technology

　　In the vast universe of science, organic chemistry is like a bright star, leading us to explore the mystery of life. As a subject of studying carbon compounds, organic chemistry, with its unique charm, closely links all fields of natural science and reveals the material basis of life phenomena for us. Organic chemistry, an important branch of chemistry, is a subject that studies the source, structure, properties, separation, preparation, application and related theories of organic matter. “Organic matter” here refers to compounds containing carbon elements, such as alcohols, aldehydes, carboxylic acids, etc. It is worth noting that although organic matter mainly comes from organisms, with the development of science and technology, people have been able to synthesize many artificial organic compounds with biological activity, such as drugs, dyes, plastics and so on.

　　The main research contents of organic chemistry include: synthetic chemistry of organic matter; Metal organic chemistry and elemental organic chemistry; Physical and theoretical organic chemistry; Stereochemistry; Bioorganic chemistry; Natural product chemistry; Chemistry of organic materials.

　　The importance of organic chemistry:

　　1. Basis of life: From the origin of life to the growth and development of organisms, carbon always plays a vital role. Through the study of organic chemistry, we know the structure and function of biological macromolecules such as protein, nucleic acid, sugar and lipid, which are the material basis of life.

　　2. Key in the field of medicine: Many drugs and bioactive substances are organic compounds, such as antibiotics, antiviral drugs and hormones. By studying the structure and function of these substances, scientists are constantly discovering new treatments to protect human health.

　　3. The core of industrial production: Organic chemistry plays an important role in industrial production. For example, in the process of petroleum refining, heavy hydrocarbons in petroleum can be converted into light hydrocarbons by the action of catalysts; In the process of plastic synthesis, organic chemical reactions provide a steady stream of power for the plastic industry. Although organic chemistry has made remarkable achievements in many fields, it still faces many challenges.

　　First of all, in environmental protection, how to realize green synthesis and reduce the discharge of harmful waste is an urgent problem for organic chemists.

　　Secondly, in the field of medicine, how to improve the selectivity of drug molecules and reduce side effects is also a difficult problem to be solved urgently. Faced with these challenges, organic chemists are constantly exploring new reaction mechanisms, catalysts and synthetic methods. I believe that in the near future, organic chemistry will bring us more surprises and inject new vitality into the development of human society. Organic chemistry, as a discipline to study the molecular cornerstone of life, plays an important role in natural science. Let’s walk into this wonderful world hand in hand, grow in exploration, break through in innovation, and jointly write a bright future of organic chemistry.

　　Ski pants are by no means ordinary pants, but your right-hand man for adventure in the snow, allowing you to travel freely in the world of white clothes. Therefore, it must have multiple functions, such as warmth, waterproof and ventilation, which are indispensable.More importantly, put Pink baggy snow pants It is imperative for us to make thorough analysis and maximize its social function. https://ninetyroll.co/

　　When choosing ski pants, I pay special attention to the material. The importance of waterproof fabric is self-evident. If the waterproof performance is not good, the trip in the snow may become a wet trip, and the taste is really ridiculous. Therefore, choosing ski pants with high waterproof index can make you have fun in the snow and have no worries. Thermal performance is also crucial. When skiing, the body loses heat quickly.

　　If the ski pants are not warm enough, it will easily make people cold. Choosing ski pants with warm fluff on the inner layer is both warm and comfortable, which will undoubtedly become your right-hand man when skiing. In addition, air permeability can not be ignored. Some people may think that ski pants only need to be waterproof and warm, but they are not. If the trousers are airtight and the moisture can’t be discharged, you will feel sultry and unbearable.

　　Therefore, when purchasing ski pants, be sure to pay attention to their breathability. Finally, comfort and design can not be ignored. Ski pants should be elastic enough to move freely when skiing. At the same time, pockets, zippers, etc. should also be designed reasonably to facilitate the storage of items. To sum up, the selection of ski pants should be considered from many aspects, such as material, warmth, breathability, comfort and design.

　　Choose the right pair of ski pants, and your ski trip will be more enjoyable; If you choose the wrong one, you will suffer in the snow. Therefore, everyone must be careful when buying ski pants!

　　We often talk about future technological trends, but sometimes we have to admit that in the pursuit of more efficient digital world, there are also many classic solutions with great times, which are gradually being eliminated by rapidly changing emerging technologies.among Personal automation It has given great spiritual support to entrepreneurs, and more entrepreneurs will contribute to this industry in the future. https://www.azilian.co

　　To this end, Ai Faner will launch a series of articles around the theme of “Good Design Abandoned by the Times” to discuss the exquisite structural designs that have accompanied us day and night, their past, present and future stories. This is the first article.

　　The knob has been half buried in the grave, which was ten years ago, and no one will believe it.

　　You may remember that when you were a child, almost every household had an old-fashioned radio, and the silver cylindrical knob was evenly engraved with scales. One of the joys of childhood is to lie on one side and fiddle with the knob. The sizzling sound of electricity in the radio, the babbling sound of human voice and music appear alternately with the rotation, as if the sound waves with emotions have been transmitted alternately and endlessly.

　　Maybe not on the radio, but I’m sure you’ve felt something similar.

　　The knob is not an invention that changes the world, but it can do what keys can’t.

　　As a mechanical structure, it is impossible to test which equipment the knob first appeared on. Maybe it was a telegraph in the last century? Or some oscillograph? It may also be the later radio or TV. Like many buttons, it was naturally born on electronic equipment, and then gradually became popular, becoming a part of the electronic dashboard, and it has been used as a controller all the way to this day.

　　The knob itself is very delicate, which is different from pressing a switch to output only one quantity. The knob may correspond to several quantities or a limited range of “0-10”. For example, the common volume knob will allow the user to make any adjustment within a certain value, and the desired volume can be obtained with a slight turn, which can not be achieved by pressing the up and down buttons all the time.

　　Because of this feature, when you adjust the volume by turning the knob, you don’t look at the scale information carefully (some don’t even have a scale). Maybe you don’t care about the size of the number at all, but you will “find” a just right sound with your ears.

　　A similar experience can also be felt from the desk lamp. We will adjust the brightness through rotation, but in fact we are also relying on our eyes to find the right light source, instead of paying attention to a specific digital scale or color temperature range.

　　If it is a product that really pursues texture, it will also pay attention to the damping feeling of the knob, in order to allow users to adjust to their desired position more accurately through the feel, whether it is a paragraph-like jam or a smooth transformation, it will make people fondle.

　　A typical example is the first batch of Atari game consoles in the 1970s. At that time, the joystick and direction keys were not yet born, and all the controls were handed over to the knobs. Although it can only control two directions, the rotation degree of the knob can output more accurate moving variables than the keys, which is enough to play a simple 2D plane game like PONG.

　　This is the immersive experience brought by the knob, which can make people focus on the information itself. Or, under this continuous control, we will naturally have this intuitive behavior, because our ears and eyes have already responded to the results in advance.

　　But even with such exquisite design, the knob has rarely appeared on mobile phones or computers. Now, let’s not talk about common devices. Smartphones and laptops are basically invisible to us. Even in the era when the touch screen has not become a standard configuration, the knob is not the first choice for most products.

　　But the knob is not completely extinct. You can still see it in some specific places, such as the ECG monitor in the hospital or the mixer in the school broadcasting room. There are still controllers of various sizes on such professional instruments. Some consumer electronics products also recognize the intuitive and easy-to-use characteristics behind the knob, so it also exists as an auxiliary interaction scheme.

　　If those digital and graphical controllers pursue unity and high efficiency, then the knob and so on are preserved, which may be our original unconscious cognition of this operation mode.

　　Good design should dance with the times

　　It is quite logical that Digital Crown will appear on Apple Watch. According to Jony Ive, the chief designer of Apple at that time, he hoped to create a “strange familiarity”-both the meaning of crown in traditional watches and the form of auxiliary interaction of smart watches.

　　I still remember a very clear detail. When setting the alarm clock interface through Apple Watch, you slowly push the Digital Crown knob, and the numbers will jump one by one. Once the speed of pushing is fast, the numbers will change rapidly with this frequency, which is exactly the same as the sense of control brought by the crown of the traditional watch, and this knob can be operated with only one finger.

　　At its root, Apple Watch is not like a smart phone. Its screen size is only about 1.5 inches. Two fingers can cover the whole screen, and it is impossible to control it accurately.

　　In order to avoid the problem of visual occlusion, the original virtual crown scheme was directly abandoned, and the Digital Crown appeared in a physical form. At the same time, there was a pressure-sensitive touch control developed based on Taptic Engine, which also continued to the later iPhone.

　　The Dial input device on Surface Studio may be regarded as the most creative attempt in the Microsoft Surface series. Anyone who picks up this huge cylinder will basically understand how to use it as a part of the “button” and as a “knob”. Although this is not an interactive scheme for mass consumers, I believe that most people will like this simple, direct and attractive design as long as they get started.

　　The structure of protein molecule determines its properties.As a representative of the industry, Antibody Phage Display Service It is necessary to set a certain example for peers and lead the way in product quality. https://www.alphalifetech.com/

　　Being bisexual.

　　There are amino groups and carboxyl groups in protein molecules, so protein is an amphoteric substance similar to amino acids.

　　2. Hydrolysis reaction can occur.

　　Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

　　When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

　　3. Having the property of colloid.

　　Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution. When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

　　The precipitation of protein.

　　A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

　　Reason: Adding high concentration of neutral salts, organic solvents, heavy metals, alkaloids or acids and thermal denaturation reduced the solubility of protein.

　　Protein precipitated by salt can still be dissolved in water without affecting the original properties of protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.

　　The supercoiled structure formed by the further spiral of DNA molecules is called the tertiary structure of DNA.The data shows that, Chemical Custom synthesis Its development potential should not be underestimated, and it is also the inevitability of its existence. https://www.all-chemistry.com/

　　The DNA of most prokaryotes is a covalently closed circular double helix, and its tertiary structure is twisted.

　　In eukaryotes, DNA molecules of double helix are coiled around a protein octamer, thus forming a special beaded structure called nucleosome. Nucleosome structure belongs to the tertiary structure of DNA.

　　In the cold winter, skiing is a very popular outdoor sport. Ski pants are one of the essential equipment in skiing. So, when you wear ski pants, do you need to wear pants inside? This question may vary from person to person, depending on personal preferences and needs.The data shows that, snowboard pants baggy Its development potential should not be underestimated, and it is also the inevitability of its existence. https://ninetyroll.co/

　　Do you still need to wear pants under ski pants?

　　First of all, let’s know the characteristics of ski pants. Ski pants are mainly characterized by their waterproof, windproof and warm-keeping properties. Generally speaking, the outer layer of ski pants is made of waterproof material, which can prevent the infiltration of snow water and keep warm. The inner layer is usually made of warm-keeping materials such as fluff or wool to increase the warm-keeping effect. Therefore, the ski pants themselves have certain warm-keeping performance.

　　So, why would anyone wear pants under ski pants? There are several possible reasons. First of all, some people may think it is more warm. Especially in high-intensity skiing, the body will emit a lot of heat. If you wear a pair of pants under the ski pants, you can effectively stop the heat loss and keep your body warm. Secondly, for some people who have just started to learn skiing, wearing a pair of trousers can provide extra protection to prevent injuries when they fall. Finally, some people may think that wearing pants under ski pants can provide extra security for habit or psychological reasons.

　　Do you still need to wear pants under ski pants?

　　However, some people do not recommend wearing pants under ski pants. First of all, doing so may add extra weight and burden, which will affect the flexibility and comfort of skiing. Secondly, if you wear pants when you fall, it may cause friction between the skin and the snow, increasing the risk of injury. In addition, for some professional skiers, they may pay more attention to portability and flexibility, so wearing pants under ski pants may become a burden.

　　To sum up, whether it is necessary to wear pants under ski pants depends on personal needs and preferences. If you are a beginner in skiing or think it is necessary to increase warmth, it may be a good choice to wear pants under ski pants. But if you pay more attention to lightness and flexibility, or think that doing so may increase the risk of injury, then you may prefer not to wear pants under ski pants.

　　It should be noted that whether you choose to wear pants under ski pants or not, you should consider the warmth and comfort of the material when purchasing. At the same time, make sure that the pants you choose will not affect your normal sports and activities.

　　Do you still need to wear pants under ski pants?

　　In addition, if you choose to wear pants under ski pants, you should also pay attention to the following points:

　　1. Choose suitable materials: Try to choose lightweight and breathable materials to avoid adding extra weight and burden.

　　2. Pay attention to the right size: make sure that the pants you wear are not too tight or loose to avoid affecting comfort and flexibility.

　　3. Consider waterproof performance: If you plan to do activities in the snow for a long time, you should choose pants with waterproof performance to prevent snow water from penetrating and keep your body dry.

　　4. Keep safe: Although wearing pants under ski pants may increase some protection, you should still pay attention to keep safe and try to avoid unnecessary falls and collisions.

　　In a word, whether to wear pants under ski pants depends on personal preferences and needs. No matter what choice you make, you should consider the warmth and comfort of the material, and ensure that the equipment you choose will not affect your normal sports and activities.

　　The structure of protein molecule determines its properties.according to recombinant proteins Industry veterans said that its development will still be in a good situation. https://www.alphalifetech.com/

　　Being bisexual.

　　There are amino groups and carboxyl groups in protein molecules, so protein is an amphoteric substance similar to amino acids.

　　2. Hydrolysis reaction can occur.

　　Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

　　When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

　　3. Having the property of colloid.

　　Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution. When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

　　The precipitation of protein.

　　A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

　　Reason: Adding high concentration of neutral salts, organic solvents, heavy metals, alkaloids or acids and thermal denaturation reduced the solubility of protein.

　　Protein precipitated by salt can still be dissolved in water without affecting the original properties of protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.

　　Nucleic acid is a long-chain polynucleotide compound with no side chain formed by connecting nucleotides through 3′,5′- phosphodiester bond.For these reasons, I think inhibitors The situation is still optimistic, and the market is still in a blue ocean stage. https://www.all-chemistry.com/

　　Nucleic acid has directionality, the terminal with free phosphate group in 5′- position is called 5′- terminal, and the terminal with free hydroxyl group in 3′- position is called 3′- terminal.

　　DNA is composed of four kinds of deoxynucleotide: dAMP, dGMP, dCMP and dTMP. Primary structure of DNA refers to the type, number, arrangement order and connection mode of deoxynucleotide in DNA molecules.

　　RNA consists of four ribonucleotides: AMP, GMP, CMP and UMP. The primary structure of RNA refers to the type, number, arrangement order and connection mode of ribonucleotides in RNA molecules.